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Department of chemotherapy and technological innovations

The Department of Chemotherapy and Technological Innovations of the N.N. Petrov National Medical Research Center of Oncology offers conventional and high-technology systemic pharmacological anti-tumor treatment of patients with disseminated solid tumors.

The Department treats patients with malignant tumors of different sites:


  • skin melanoma
  • germ cell tumor (seminoma, non-seminoma, germinoma, dysgerminoma)
  • bone and soft tissue sarcomas (osteosarcoma, Ewing sarcoma, chondrosarcoma, liposarcoma, leiomyosarcoma, schwannoma, malignant fibrous histiocytoma, etc.)
  • colorectal cancer
  • stomach cancer
  • lung cancer (small-cell lung cancer and non-small cells lung cancer)
  • neuroendocrine tumor (carcinoid tumors, neuroendocrine carcinoma, apudoma, etc.)
  • breast cancer
  • ovarian cancer
  • endometrial cancer
  • kidney cancer
  • prostate cancer
  • bladder cancer
  • etc.

The Department uses the following treatment modalities:

  • chemotherapy, including multiagent chemotherapy, high-dose chemotherapy, continuous infusion of cytostatic agents using infusion pumps;
  • immunotherapy: treatment with cytokines (IL-2 and interferon alfa), checkpoint inhibitors, tumor vaccines;
  • targeted therapy;
  • hormone therapy.

The Department hosts clinical trials of new high-potential antitumor drugs and therapies. For many years the Department has been developing modalities of treatment of malignant neoplasms, which are based on the latest global achievements in oncology.

The Department of Chemotherapy and Technological Innovations is the main clinical site of the Cancer Immunology Research Division of the Center. The physicians of the Department are recognized - nationally and globally - as leading specialists in immunotherapy which has been used at the Department since 1998. The specialists of the Department are developing and translating to clinical applications innovative methods of immunotherapy, in particular cancer vaccines. Fifteen cancer vaccines and antitumor vaccines have been developed so far.

The specialists of the Department of Chemotherapy and Technological Innovations work in close cooperation with the surgical departments of the Center to treat prostate cancer, bladder cancer, ovarian cancer, endometrial cancer and breast cancer.

The staff of the Department are experts in treatment of melanomas, germ cell tumors, and soft tissue and bone sarcomas.

The Department takes active part in development of the national guidelines for treatment of malignant neoplasms.

The Department is headed by -Dr Svetlana A. Protsenko, D.Sc. (Medicine).

The staff of the Department are highly qualified specialists and members of the world’s largest professional organizations, such as the Russian Society of Clinical Oncology, the American Society of Clinical Oncology, the European Society for Medical Oncology, the European Association of Dermato-Oncology and the Eurasian Federation of Oncology.

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